Metronidazole - what is it?

  • Metronidazole - what is it?
  • Side effects

Metronidazole Metronidazole - an antibiotic that destroys harmful bacteria in the body. Metronidazole is used to treat bacterial infections of the genital organs, gastrointestinal and respiratory tract, skin and joints. Metronidazole is not used to treat vaginal fungal infections Fungal infection: prevent and defeat Fungal infection: prevent and defeat .

Important information about metronidazole

Take metronidazole strictly in accordance with the doctor's instructions for the recommended period.

In no case do not interrupt the course of treatment at the first signs of improvement or disappearance of symptoms: this does not mean that you get rid of the infection.

In addition, failure to comply with dosage and irregular intake of metronidazole can lead to the formation of bacterial resistance to the antibiotic Antibiotics - if they help you in the foreseeable future? Antibiotics - will they help you in the foreseeable future? .

Metronidazole is not used to treat common viral infections, such as the common cold or the flu. During the trea

tment with metronidazole, alcohol should be avoided, plus 48 hours after the last intake, because acetaldehyde accumulation may occur due to a violation of ethanol oxidation. As a result, there may be side effects: increased heart rate, redness and itching of the skin, nausea and vomiting.

What you need to know before taking metronidazole

Metronidazole should not take persons suffering from intolerance to metronidazole or drugs, as well as pregnant women( up to 12 weeks), and lactating women. Be sure to tell your doctor if you are expecting a baby or are planning a pregnancy.

Also tell your doctor if you are allergic to any drugs, as well as on the following diseases:

  • diseases of the gastrointestinal tract, such as Crohn's disease;
  • diseases of the hematopoietic system, for example, anemia( lack of red blood cells) or leukemia( lack of white blood cells);
  • impaired coordination of movements, organic lesions of the nervous system( including epilepsy);
  • severe hepatic and renal failure Renal failure - when treatment is vital Renal failure - when treatment is vital ;
  • neural disorders.

Metronidazole can not be taken in the first trimester of pregnancy. The use of the drug in the II and III trimesters is possible only in cases where the intended benefit to the mother exceeds the potential risk to the fetus.

If it is necessary to use metronidazole during lactation, breastfeeding should be stopped for a while, as the drug penetrates into breast milk and can harm a child's health.

Dosage and method of administration of metronidazole

In trichomoniasis, adults are given a single dose of 250 mg in the morning and evening for 10 days. After the completion of the course of treatment, several control laboratory tests should be conducted( every 3-4 weeks).

With amoebiasis, adults are prescribed 250 mg 3 times a day. The course of treatment is 5-10 days;The dose is set at 35-50 mg / kg / day for children. The daily dose should be divided into 3 divided doses. The course of treatment is 10 days.

With giardiasis Giardiasis - a full examination of Giardiasis - full examination is recommended is recommended for adults and children over 10 years of age prescribed 500 mg / day;Children aged 6-10 years - 375 mg / day;2-5 years - 250 mg / day. The daily dose should be divided into 2 divided doses. The course of treatment is 5-10 days. After the end of the course of treatment, several control laboratory tests should be conducted. If necessary, treatment can be repeated after 4-6 weeks.

For treatment of infectious diseases caused by anaerobic bacteria, adults and children over 12 years of age, the drug is administered intravenously every 8 hours for 100 ml of a 0.5% solution( 500 mg).Infusion is carried out at a rate of 5 ml / min. The maximum daily dose for intravenous administration is 4 g. The course of infusion therapy is 7-10 days, if necessary = 2-3 weeks. Children under 12 years dose for intravenous administration set of calculation of 7.5 mg / kg body weight( 1.5 ml of a 0.5% solution of metronidazole) every 8 hours. The drug is administered intravenously, slowly. Metronidazole is also prescribed by mouth in a single dose of 250 - 500 mg.

For prevention of infections caused by anaerobic bacteria( before surgical operations on the abdomen, in the obstetric practice), the application of the metronidazole solution infusion should begin within 5-10 minutes before surgery. Adults and children over 12 years of drug is administered at a dose of 500 mg( 100 ml of 0.5% solution) / drip slow infusion is repeated after 8 hours. The drug is used prophylactically no more than 12 hours after surgery. Children under the age of 12 years, the dose for intravenous administration is set at the rate of 7.5 mg / kg body weight( 1.5 ml of a 0.5% solution of metronidazole).

Metronidazole is also prescribed by mouth. Adults and children over 12 years of age receive the first single dose of 1 g( 4 tablets of 250 mg), then 250 mg 3 times daily during or after meals, before the onset of pre-operative fasting;Children from 5 to 12 years of 125 mg every 8 hours for 2 days.

Store metronidazole at room temperature in a dry, dark place. Do not use after the expiration date printed on the package.

Can I skip the use of metronidazole?

If you forget to take metronidazole, correct this oversight as soon as possible. If it is time to take the next dose of the drug, do not double the dose to compensate for the missed medication.

What should I do if I exceed the dose of metronidazole?

In case of an overdose of metronidazole, consult a doctor immediately. Symptoms of metronidazole overdose: seizures, peripheral neuropathy;After a single oral intake of 15 g of metronidazole, nausea, vomiting and impaired coordination of movements are possible.

Specific recommendations for the treatment of metronidazole

During treatment with metronidazole should avoid alcohol, plus 48 hours after the last dose, because the accumulation of acetaldehyde may be due to violations of ethanol oxidation.

Side effects: heart palpitations, redness and itching of the skin, nausea and vomiting.

Carefully read the information on the packaging of medicines or foodstuffs to make sure that they do not contain alcohol.

Taking antibiotics can cause diarrhea, which may indicate a new infection. If diarrhea occurs, stop taking Metronidazole and consult a doctor. Remedies for diarrhea can be taken only on the advice of a doctor.

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